How often are DPP-4 inhibitors (gliptins) used for the management of glycemic control in Type 2 DM in Nepal?

More Lokendra Bahadur Sapkota's questions See All

Is Short Form SF12 , HRQOL is free for use?

or do we need to take permission or it's free.

10 January 2024 7,829 0 View

What are the relevant statistical tests to analyze multiple categorical outcome variables with predicotr variables?

Please suggest me relevant statistical tests to analyze relationship of multiple categorical outcome variables at a time with predictor variables.

14 October 2023 3,606 1 View

How can make rat brain hard for fixing in microtome immediately after extraction keeping cells alive for primary culture?

Is there any specific protocol to extract arcuate nucleus from rat hypothalamus using microtome, keeping cells alive for primary culture?

23 February 2023 1,556 0 View

How can my taxonomic description better while describing Millipedes species belonging to Order: Spirostreptoda?

I am trying to write a taxonimic description on some of the Nepalese Millipede species belonging to order Spirostreptida. I am feeling difficulties while writing description. Can you have any idea...

31 December 2022 7,576 0 View

How to simulate crack growth in Abaqus using Paris law for nitinol (super elasticity) material??

I am trying to simulate crack growth in ABAQUS using Paris law. But I am getting super elasticity convergence error. I am using the direct cycle step. I can easily simulate linear materials. But I...

07 February 2022 4,376 2 View

How do you prepare a high osmolarity 4% PFA for fixing 300 um brain slices?

I am trying to use 300 um hippocampal sections for immunohistochemistry but the antibodies have not penetrated deep enough (

25 October 2021 1,325 0 View

How to get a high virus titre of Chikungunya virus (CHIKV) propagated on Vero cells?

I propagated CHIKV on C6/36 before and harvested on different days of infections, though the results of immunofluorescence assay are highly positive for infection, I cannot get good plaque...

09 August 2021 4,217 1 View

Hall effect measurement of CIS films?

What would be the best metal contact for Copper Indium Selenide (CIS) to measure the Hall effect? Film thickness is about 2 micron and it is copper poor (Cu/In = 0.9).

14 March 2021 3,339 2 View

[SAP2000 related] I wonder why there is no any effect in the analysis result when I change the different parameters while modeling a frame structure?

(i) I have modeled a simple 2D frame structure (2 columns and 1 beam). I would like to see the variation in the result by varying the different parameters such as, sizes of confinement bars,...

06 October 2020 9,704 5 View

If a word file is shared with a person via Google Docs, can the recipient have access to the other files?

We can share and edit 'word' files online via Google Docs. It is an easy and convenient way of creating, sharing and editing the same document online between the concerned users. However, my...

22 September 2020 843 3 View

Culture fibroblasts with or without FGF2?

I'm new to primary human fibroblast culture and I'm studying aging using cells from old and young donors. Some research groups have used media supplemented with FGF2, so I cultured cells in the...

29 July 2024 3,030 2 View

Is there a good "no frills" search tool for highlighted text?

I am looking for a no frills search tool that will find highlighted text in pdf and epub files. I just want something that will just take me to the next highlighted word or phrase in the way a...

07 July 2024 190 5 View

Would it be possible to determine how many Cys I have based on Ellman's assay?

I want to predict the DAR ratio based on the number of cys available for conjugation to Cys residue. I use Ellman's assay to predict the concentration of Cys after TCEP reduction. I gain a...

02 July 2024 612 6 View

Does anybody know of a cell type with enriched expression of CD63, CD9 and CD81?

I need an appropriate positive control for WB antibodies I am using to confirm the presence of exosomes in samples. The thing is I am having reproducibility issues, and I would like distinguish...

19 June 2024 4,210 3 View

How to mimic diabetic conditions in cell culture?

Is there a protocol to establish diabetic conditions in pre-osteoblasts cell culture?

18 June 2024 9,306 2 View

IL-2 for PBMCs ex-vivo stimulation, best Concentration?

Hello everyone, I am isolating PBMCs and stimulating them using different stimulation conditions. my question is, I want to add IL-2 to the medium for better viability after stimulation, Would you...

16 June 2024 928 1 View

How does the presence of diabetes affect the prognosis of myocardial infarction?

Comprehensive Overview of Myocardial Infarction: Etiology, E... How does the presence of diabetes affect the prognosis of myocardial infarction?

15 June 2024 1,038 3 View

Is the prevalence of shoulder frozen is higher in Diabetic patients?

the prevalence of shoulder frozen is much higher in diabetic patients than non diabetic, and what will be the cause? There is many reports but still not will understood.

10 June 2024 3,270 3 View

Are these round cells healthy, or should they all be elongated fibroblasts?

I started a cell culture with a mix of suspended and adherent cells (presumably fibroblasts) on May 10th. After a week, I treated them for adherent cells only. On May 24th, most of the adherent...

02 June 2024 4,903 5 View

Peer support in adolescents with type 1 diabetes?

Type 1 diabetes, the effect of peer support in self care efficacy, emotional well being

27 May 2024 4,325 0 View

Deepu Sebin

From my limited exposure in Nepal (2015), I am yet to see a patient on DPP4. I have seen atlease 100+ DM patients.

From my limited exposure in Nepal (2015), I am yet to see a patient on DPP4. I have seen atleaset 100+ DM patients.

Akm Humayon Kabir

I have treated atleast 300 patients with type -II DM especially who are obese and uncontrolled Diabetes with metfomin with /without insulin/secretigogue very good result that is very good and stable glycemic controll ,weight nutral/weiggt reducing effect and less hypoglycemic side effect. thanks