How interferes the ethylene glycol in the antigen-antibody bond?

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Omar Gonzalez-Ortega

Since many hydrogen bonds are involved, in general, in molecular recognition; I would expect ethylene glycol to compete for these bonds. If enough ethylene glycol is added I would expect that both antigen and antibody interact with it preventing their agglomeration.

Antonio La Gioia

Thank you, Omar. I would like to know whether the competitive mechanism in addition to the inhibition of the antigen-antibody bonds could explain their reversibility

I think so especially for higher concentrations of ethylene glycol