I want to prepare nano encapsulation of hydrophobic drugs using polyethylene glycol (molecular weight below 1000) as a coating agent. Which method will be good option like inter facial polymerization, phase inversion precipitation, in-situ polymerization and solvent evaporation?
Abdelkader BOUAZIZ
Dear Aloke Purkait,
PEG-diblock copolymers are used in this situation, in which the second block forming the copolymer should have some affinity to the hydrophobic drug to be loaded. You may obtain good documentation using the keyword 'stealth liposome'. Regards
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