HPLC method validation?

Dear Dr's and researchers what is the best parameters to make method for a new Schiff base derived from benzocaine?

10 November 2018 6,738 8 View

2-AZETIDINONE preparation from Schiff base?

are their any chemical compound that used to synthesis 2-AZETIDINONE from Schiff base other than chloroacetyl chloride?

10 November 2017 6,314 4 View

Schiff base preparation?

Dear Dr's I prepare Schiff base; firstly lemons color appear, after 4 hrs "i forget it more than 1 hour" the color change to brown; are their a relationship between time and color?

09 October 2017 2,708 6 View

Molar ratio?

anyone can help me to use conductivity method to determine molar ratio of Schiff base-metal complex? i need reference please?

04 May 2017 755 0 View

Sodium borohydride?

Dear Dr's: I would like to ask about the effect of NaBH4 on a schiff base have an ester group; does the ester affected by NaBH4?

01 February 2017 5,358 4 View

White Schiff base ?

Are their a Schiff base with white color?

11 December 2016 7,243 1 View

Indicator film used to detect some metals by make complexation with it?

09 October 2016 7,036 3 View

No title

uv

05 June 2016 5,121 0 View

Is carbonic acid an organic acid or an inorganic acid?

if i say H2CO3 ( called carbonic acid) does'n exist but it is a solution of CO2 dissolve in water and both of them are inorganic compounds so it is an inorganic compound???

10 November 2015 9,376 3 View

Dear Dr's i hope to aske about fluorescence?

01 January 1970 2,732 3 View

What solvent can I used for Paal Knorr reaction between 6-amino hexanoic acid and 2.5 hexanedione?

I am try to make the Paal Knorr reaction between 2.5 hexnedione and 6-amino hexanoic acid, my problem is type of solvent to use, because 6-hexaminohexanoic acid is soluble in water but I am not...

02 March 2021 4,443 2 View

Ester cleavage conditions?

Hi all, I need to cleave the ester in Ethyl 2-amino-1H-imidazole-5-carboxylate to make the carboxylic acid and retrieve the product from solution to use in downstream applications of linking to...

01 March 2021 8,766 3 View

Is CD44 degraded in lysosome together with hyaluronan after CD44 mediated endocytosis of hyaluronic acid?

Also when RHAMM binds hyaluronic acid, they get internalized, will RHAMM also be degraded? Or both CD44 and RHAMM will be transferred back to the cell membrane? Asking for breast cancer cell line...

01 March 2021 8,169 2 View

I want to performe MALDI-TOF MS for bacterial identification, I would appreciate it if anyone can tell me the matrix solution preparation protocol ?

based on what I've studied on multiple papers, for peptide and protein identification Alpha-cyano-4-hydroxycinnamic acid (CHCA) is an appropriate matrix to use, I also know that the CHCA powder...

26 February 2021 6,799 3 View

Can I use acetic acid with an ELITE WAX Perkin Elmer column for Gas Chromatography?

Hi! I would want to know if I can use acetic acid with an ELITE WAX Perkin Elmer column for Gas Chromatography. This column has a polyethylene glycol phase, but I can't find the manual to check...

22 February 2021 730 2 View

Can you perform the Murexide test on samples fixed in Formalin?

I have a fixed sample and would like to use the murexide reaction to test for uric acid composition. I no longer have fresh samples

22 February 2021 1,328 1 View

Is there an ideal incubation time of RGO-modified SPCE before subsequent use, i.e., electrochemical characterization or further modification?

I notice that upon washing and air-drying of my RGO/SPCE surface and characterizing again via DPV, the current response towards ferricyanide probe significantly decreases. My worry is that the...

22 February 2021 5,324 3 View

What is the best etching method for Mg-Ca alloy?

I have used Picral etchant (4.2 g Picric acid, 10 mL Acetic acid, 70 mL Ethanol, 10 mL distilled water) but it didn't work. Is there any alternative?

21 February 2021 2,558 5 View

Protocol for membrane extraction E. coli?

Hello! I am interested in determining whether a poly-unsaturated fatty acid I have engineered E. coli to produce is being incorporated into the membrane of the cells or if it is simply a free...

21 February 2021 7,447 2 View

What is the stability of 2 3-dihydroxyquinoxaline in acidic water?

I'm developing a UHPLC assay, and the fluorescent product is 2,3-dihydroxyquinoxaline. The reaction to produce this requires hydrochloric acid (about 1.2 M). Will storage in this acidic...

20 February 2021 5,820 4 View