How do you calculate the fractional inhibitory concentration index (FICi) of two combinations of drugs, if their MICs are unknown?

For example, drug A's MIC is reported as >16microg/ml and that of B as >12.5microg/ml. The combined MIC that brings about synergy is 0.5microg/ml for drug A and 0.78microg/ml for drug B. How...

08 September 2016 3,916 4 View

Image Classification: How to collect ground truth data for training and validating of historical imagery?

Image Classification: How to collect ground truth data for training and validating of historical imagery?. I need to analyze imagery captured in 1985 to 2015 at 5 year intervals. I only have...

01 January 1970 7,737 3 View

IHC on mouse liver hepatocytes?

Can anyone help me choose primary antibodies for mouse liver hepatocytes and also in conjunction Cd8 cells. Also Cd3 cells. I want to look at hepatocytes and adjacent immune cells in mice with...

01 March 2021 6,953 1 View

How can i select suitable gene sequence at Ring stage of Plasmodium Falciparum for primer design?

I am new to PCR. We are working on PCR based amplification of targeted DNA sequence of Plasmodium Falciparum. For that, We are targeting the Ring stage of the parasite. I want to know on which...

15 December 2020 6,954 3 View

Can anyone tell me the name of these parasites which I got from a marine fish?

I got these parasites from eye and intestine of a marine fish. Thank you.

09 December 2020 7,752 2 View

What is a diagnostic resistance in malaria?

For malaria research experts/Scientists I am experiencing a full explanation of the following concept: I have been looking at the biological threat of malaria to the control efforts, where the...

16 October 2020 1,563 4 View

What is the status of malaria vaccine?

Malaria is the highest killer disease in Africa, yet no vaccine has been developed against it. Any hope in sight?

05 October 2020 5,670 7 View

Are 12-week-old C57 mice resistant to cerebral malaria?

14 September 2020 460 4 View

Does it make sense to do the soil nutrient analysis directly on the field?

The soil analysis requires the sample to be transported to a laboratory. This means work and costs. In the laboratory the process steps take place: Soil preparation, analysis and documentation of...

10 September 2020 5,302 3 View

Someone recommend to use CFSE to stain parasites as Trypanosoma or Leishmania species to detect cells infection?

I have seen that some groups use CSFE to stain some parasite species before infect cells to detect percetage of infected cells. Could I use CSFE to stain Trypanosoma cruzi and measure infection in...

15 August 2020 1,898 2 View

Hydroxychloroquine Protonation in Blood and Cells - inconsistent information on claimed alkalinization inside targets, emphasis on Coronavirus?

Some researchers have claimed that Hydroxychloroquine (HCQ) can enter cells and make the environment more "alkaline" by soaking up protons. Many publications discuss only 2 nitrogen atoms that can...

08 August 2020 6,262 3 View

X-Ray fluorescence technique can be used for soil nutrient detection? Can we get concentrations of Macro and Micro nutrients accurately?

I want to perform soil nutrient analysis. I want to use X-ray fluorescence technique instead of chemical analysis that is conventionally used in lab. Is it reliable to use X-ray fluorescence for...

28 July 2020 8,813 3 View