How do you prepare 1 mM FcMeOH?
It is insoluble in water and it tends to build up flakes after some time.
I reckon that using FcMeOH with flakes floating around in order to study the kinetics parameter of a substrate is not a good thing.
Could provide any literature in electrochemistry that shows how to prepare FcMeOH?
You may try to first dissolve it in an organic solvent such as DMF or DMSO to make a concentrated solutin, then dilute it into water
Hello Saiful,
Do you mean ferrocenemethanol (ferrocene with a -CH2-OH group on one the Cp rings)? You can purchase it or make it by reducing the carboxylic acid (via the ester) or aldehyde. It is water soluble, and you should be able to get 1mM of it.
Try warming the solulion slighty to dissolve or sonicaing to break up the chunks of the material.
If you give us a more specific description of the molecule, we will be able to assist more.
Cheers,
-Dr. Kyle Grice
I actually had the same problem yesterday - I was trying to prepare 10 mM ferrocenemethanol and there were orange flakes in the solution. So I diluted it to 5 mM, but it didn't dissolve as well... So I gave up and used very similar redox probe (also uncharged) - 1,1' - ferrocenedimethanol (it has two -CH2-OH groups), which is soluble in water :)
Thank you so much for all the advice. I tried ferrocene carboxylic acid actually but still I did not get a great result. So, I found this one paper stated that they have prepared ferrocenemethanol by adding 2% of ethanol into the solution and I did just that and it works. Marcin, if you would like to use ferrocenemethanol, you can use this method as well. Thank you so much again and sorry that I did not check my RG for quite a long time
Hello Sajid. My apologies for not coming back to you as soon as possible. Ferrocenemethanol is not 100% soluble in water. So, some research groups add 2% of ethanol in order to have a completely soluble ferrocenemethanol. I am not sure if I can recall the name of the paper. Do tell me if you are still interested and I will try to search for the paper. But that is the reason why. From my research, I found that there was no more FcMeOH flakes in the solution as it was complete dissolved and the limiting current of the cyclic voltammogram was according to the theoretical limiting current calculated using 4nFDCa. @sajid Rauf
Dissolving it in an aqueous solution (with 0.1 M KCl as background electrolyte) to more than 1-2 mM is difficult.
It help to sonicate it, or place it in a 50-60 C water bath.
Adding 1-2% /v/v) Methanol or DMSO helps solubilize it as well.
- Badges
- Science topic
- Similar topics
- Chemistry
- Electrochemistry