We identified a new form of an organic compound (new XRPD plot), by crystallization from EtOH/H2O 50/50 mixture. Based on a TG-DTA analysis, an endotherm is followed by weight loss that might indicate a hydrate form (calcd 5.9%, found 5.8%).
Is there another good way to confirm that it is a hydrate / exclude an ethanolate?
You can record NIR on this compound and you'll get at a sharp peak at 4800 which is to the bound water.
1.Could you not submitt your organic compound to solid state 1H NMR?
2. Maybe FTIR /assoc. OH groups vibr. approx at 3420 cm-1 might do the same
service, especially if you compared hydrate and dehydrated compound spectra....
Thank you for the answer. Unfortunately 1H NMR is beyond our reach, but FTIR is manageable. We've got the anhydrous form, so I'll try to make the comparison.
Could IR spectra may be of help?
Spectrochimica Acta Part A 60 (2004) 2611–2619
Infrared spectra of H2
16O, H2
18O and D2O in the liquid phase by
single-pass attenuated total internal reflection spectroscopy
Will ethanolates/ethanoate evaporate at the same temperature?
Will the decomposition give the same type of compounds?
If not, you can connect your TG to an MS and identify evolved species
Regards
You can record NIR on this compound and you'll get at a sharp peak at 4800 which is to the bound water.
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