Structural factors include poles of power, globalisation, patterns of internation dependency, internal legal precedents, technology etc. Thanks!

A link between a power change in countries and structural factors definitely exists. These so called structural factors possibly are the result of centuries of evolution that create certain values and morals in the indigenous people of a particular geographic area.

That being said, one can clearly that certain societies valued and fought for certain fundamental rights and freedoms, the major amongst them being the rule of law,  'free speech', right to vote and so on, as was witnessed in England when society wrested these rights from the Monarch through the 'Magna Carta'. These values manifest in the recognition of the 'rule of law', granting of fundamental rights to its citizens, and the power sharing formula usually adopted by the particular society, a factor we see reflected in the constitution of most countries, which is considered inviolable,  constituting the ultimate source of power in the country. The Constitutions of countries reflect shared values as to what is considered inviolable, while also specifying the structure of the nation and its corresponding power sharing formula. Another important factor deterministic of the type of regime that exists is also popular conceptions as to the source of laws. Where the orientation is towards a positivist kind of philosophy, this variously translates to vesting power in monarchies, and possibly divine power as exercised by monarchies or dictatorships, who are deemed chosen by God and variously the enforcers of Divine law, as would be case in some countries in the Middle East that practice Sharia, as an example.

When adverting to factors that lead to regime change, in the absence of outside intervention, where popular sentiment is in line with suppression of free speech and other democratic principles, regime change of existing dictatorships, monarchies etc.  can be hard, painful and possibly impossible to achieve. Any impetus to change may implode on itself, creating chaos and anarchy due to the power vacuum created by affording tools to disseminate messages amongst those that are not used to using them responsibly. I will qualify all of this by saying if the intended objective of regime change is to bring in a democratic form of government, the people's readiness in terms of knowing how to use freedom responsibility, respect for rule of law, cognizance and respect for certain core values such as 'fundamental rights' etc.  will be a decisive factor.

We recently published a book on the link of external factors and democratization. Please check my RG page and look for "Regional Integration and Democratic Conditionality."

Structural factors appear to be shaping domestic ones. Take the (US coined) Arab Spring, for example. There always were economic grievances as to inequalities and falling standards of living across most of the Levant, for sure, but, one wonders, why did the Arab Spring only affect the Levant but failed to touch (perhaps, except Bahrain) any of the Gulf states? Here structural factors (destructive foreign meddling) comes into equation.

Regimes are not supposed to "change" but organically evolve. Yet, structural factors can really force a change. If left to domestic factors, the tendency is evolution because even the poorest person hates to see his/her existing life conditions to be disturbed beyond repair.  

Thanks for all the responses! I look forward to more contributions

Structural factors influencing domestic factors that eventually lead to a change in government: a) changes in global flows of trade and finance (e.g., sanctions, drastic changes in commodity prices, investment outflows etc.); b) changes in international distribution of power capabilities (e.g., the rise of a powerful challenger and the govt demonstrated inability to check the rival; military buildup in the neighborhood or elsewhere and the corresponding slide in your country's relative standing vis-a-vis others); c) technological and scientific revolutions that this particular country is missing on (again, this will result in redistribution of capabilities) and any other changes in global power structures, whether military, economic, technological, cultural or any other. Whatever relates to a big change in global power distribution affects our country domestically one way or another.

I have a paper on my academia.edu page on regime change efforts in Ukraine and Syria.