How do I use Hydrogen-deuterium exchange mass spectrometry to measure the folding and unfolding rates of protein?

01 June 2022 0 10K Report

I have used HDX-MS to measure the stability of staph nuclease at different time points exchange times, but I am looking to extract the rates of folding information from my results. I have used the rate equation but I am not sure that I am correct. Any suggestions will be appreciated.

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