Hi Sai, are the clusters already defined? If so you could compute the cross-cluster entropy or variation of information (link bellow). If you want an easy means of calculating cluster membership probabilities during clustering you could use fuzzy k-means.
You could also use the Davis Bouldin Index (DBI Index), to measure the clustering performance. Some packages come with the DBI Index functions, I think MATLAB should have the function, and packages like Rapidminer have the DBI Index function inbuilt. http://en.wikipedia.org/wiki/Davies%E2%80%93Bouldin_index
Rousseeuw, Peter J. "Silhouettes: a graphical aid to the interpretation and validation of cluster analysis." Journal of computational and applied mathematics 20 (1987): 53-65.