what are the key determinants of sample size calculations for interventional study or RCTs?
what is the importance of study duration in sample size calculations in relation to the interventional study or RCTs?
need valid, reliable, and slandered method of sample size calculation for interventional study or RCTs?
How to Determine Sample Size, Determining Sample Size?
See here:
http://www.isixsigma.com/tools-templates/sampling-data/how-determine-sample-size-determining-sample-size/
or here^
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256489/
If we want to conduct a RCT on "to compare two interventions A and B in disease X.
Now how we will calculate sample size?
Any what parameters we need of population X to calculate sample size.
Dear Shakil,
I found some papers that I believe that may help you. Inside them you should find your response, see the formulas that are presented there, including the different ways to obtain them. So, there are many possibilities to calculate a sample size, but it's necessary before starting to verify mainly the factors or dependent variables.
I hope this helps,
You can also use http://www.openepi.com/Menu/OE_Menu.htm freely for sample size calculation
Sample size should be calculated based on the primary hypothesis. If the primary hypotheses are there is difference from baseline to end of intervention for each marker, then, sample size should be calculated using the standard deviation, and the assumed effect size for each marker.
Also you can visit following link: http://powerandsamplesize.com/
and
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775042/
Simon Peter Kibira Sir,
Thanks so much, the online software is a best source, I found for sample calculation of sample size, shared by your good self.
- Badges
- Science topic
- Similar topics
- Mathematics
- Statistics
- Sampling Design
- Sample Size