The adjusted odds ratio can (aOR) be estimated using a stratified table approach or regression (e.g., logistic regression). Most statistical software programs can calculate the aOR - a stratified table approach is provided by the free online program OpenEpi (www.OpenEpi.com).
To calculate the adjusted odds ratio (AOR) from given data, you can use the following steps:
Build a logistic regression model. This model will predict the probability of the outcome variable (e.g., disease) based on the exposure variable (e.g., treatment) and other covariates (e.g., age, sex).
Calculate the odds ratio for the exposure variable. This is done by exponentiating the coefficient for the exposure variable in the logistic regression model.
Adjust the odds ratio for the covariates. This can be done using a variety of methods, such as the Wald test, the likelihood ratio test, or the score test.