I have simulated crystallization of a biomolecule and found out its SASA, can SASA be corelated in any way with crystallization of that particular biomolecule?
More likely that surface area is correlated to dissolution and (potential) bioavailability. In DLS one can measure the 2nd virial coefficient as a screening parameter for optimal crystal growth . See attached.
Alan F Rawle sir, thanks for your reply. my molecule is a glycan so does that apply to glycans too? can we infer that lower the SASA value , higher will be the crystal stability?
SASA isn't related to crystal stability. The lower the SASA, then the lower the solubility rate and the lower the bioavailability. Google '2nd virial coefficient DLS'