I am working on a manuscript about pharmaceuticals that have been detected in rivers in south east England. The Q-TOF mass spectrometer results from the water samples has given each pharmaceutical a compound area. The EU Water Framework Directive Watch List requires the quantification for each substance to be monitored. Is there an equation I can use to find out the nanogram per litre for each pharmaceutical please?
No easier solution and Calibration Equations (see Tab. 5 in the attachment) are needed.
For that u required calibration curve or area of compound and standard both
You need standard for all componds, calibration curve and recovery % of all standards added in the same matrix + matrix effect calculation per standards (recovery in water vs recovery in matrix.
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