We are using the new Activa PC+S device to record LFP data during motor tasks. We are collecting kinematic data with inertial sensors. How can I sync the two systems together so they are on the same time scale?
Since Medtronic in its wisdom did not include us in the PC+S study group, I can't say whether you can get real-time time-stamps from the device itself. I would begin by assuming the DBS function is emitting 160 Hz or so monopolar pulses referenced to the device case, which are detectable by noninvasive EEG (bipolar pulses are not as easily picked up). Once you have a reliable EEG signal, you can use it to trigger sampling by the A/D digitizing your accelerometer outputs, instead of free-running sampling. I have done this for EMG signal synchronization, but not EEG, so I would be interested in your results.
If your paradigm includes switching the DBS device on and off, the easiest way of synchronizing would be coupling the motion sensors with an EMG sensor placed on top of the IPG which can detect the exact timepoints when the stimulation was changed. Another way would be to apply some external electrical stimulation like TENS of maybe a "Train of Four" device, that introduces a time-locked artifact into your PC+S Signal.
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