I used NMP as the solvent for the -OMe deprotective reaction, but in the end the solvent can't be removed due to its high boiling point. How can I do?
Or is there any other better solvent which can work ?
Salim Y Hanna
You can try to extract your product from reaction mixture using low BP.solvent that has ability to dissolve your product then evaporate the solvent, or chose solvent to extract NMP from reaction mixture.Also you can use column chromatography for separation..
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Raman Ravikumar
Multiple methanol dialysis of your NMP mixture with the protein extraction membrane would produce better result.
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