I have a putative defensin like peptide (highly hydrophobic and charged) and I would like to know, by modeling, if it is possible that the dimer form likely exist, spontaneously. So, I need a way to predict the more stable state.
Do you know of any work on the impact of capital flight on emerging economics notably on poverty and economic growth?
28 June 2018 2,347 11 View
I am preparing the inner membrane permeabilization assay and my last aliquot of E. coli ML-35 is not viable. I don´t have right now any other source to get the cells. Please, I know it is not...
09 October 2014 3,646 1 View
05 October 2014 5,944 1 View
I have dimeric and oligomeric forms of a 4,26 KDa peptide, it has positive net charge and is hydrophobic. I need to test the monomer in the antimicrobial assay.
08 September 2013 1,333 3 View
It is a cationic peptide of 40 aa. I used solid phase extraction as a concentration method, after a cation exchange that yields more than 97% purity, determined by RP-HPLC.
02 March 2013 9,974 11 View
We intend to study the interaction between peptides and polymer (like PP, PE and PS) through MD simulations using Martini force fields ( Martini 2 for PP and Martini 3 for PE, PS). We have...
08 August 2024 4,842 0 View
Hi, we have measured tryptic peptides using both DDA and DIA method on QExactive. In DDA replicates i saw unusual intensity drops occurring at the same sections of chromatograms in DDA replicates...
07 August 2024 3,218 4 View
Hello, I am currently analyzing some phosphoproteomics data, but I have peptides with multiple phosphorylation sites or phosphorylations together with carbamidomethylation or oxidation. How can I...
04 August 2024 8,432 3 View
Recently I'm trying to use Sep-pack C18 1 cc Vac Cartridge (Waters: SKU: WAT054955) to desalt digested peptides. However, the recovery rate is usually 40-60%. What is the normal recovery rate?
31 July 2024 6,544 11 View
I am reaching out to seek your valuable advice and recommendations regarding the best software tools to use for this research. Specifically, I am looking for software with a user-friendly...
22 July 2024 3,794 1 View
So i have a few peptides (synthesized by SPPS and not cleaved from resin) and I want to add a maleimide label. We have NHS-PEG-Maleimide and from literature it is evident that the free amine group...
18 July 2024 4,075 3 View
What type of experimental design do l use and what statistical tools do l use for the hypothesis. What is the position of control group in the analysis?. Thanks
18 July 2024 3,581 3 View
I am a 3rd year Computer Science student currently writing our Bachelor's thesis about finding diverse k-shortest paths in pedestrian networks. We have chosen 3 local areas as our proposed...
15 July 2024 4,289 0 View
Hi all, Do you know how to plot this figure? I found many of them in Nature journals but have not figured out how to make them. Which software/tool do you suggest? Thank you very much.
15 July 2024 8,384 2 View
Bioinformatics tools like peptide cutter
15 July 2024 6,453 1 View