Dear Victor,

it depends on how the bioprosthetic valve is mounted in your system and how you provide the pulsatile flow. For example, if all parts between the flowmeter and the valve are mostly rigid you could place one flowmeter upstream (not too far away from the valve). Because liquids themselves are uncompressable, in this configuration all volume passing the valve in both directions simultanously is passing the flowmeter. That's what we are doing in our heart simulator, regarding the fact that the sewing rim of the biological valve must be sealed. Otherwise you'll measure the paravalvular leakage additional to the transvalvular. From the recorded flow curves you could then calculate stroke, closing and leakage volumes by getting the integrals. Flowmeters for this purpose are available using ultrasound (e.g. Sonometrics).

Sorry, my mistake. The company I mean is not Sonometrics but Transonic Inc.