I am studying the cerebral aging in non - human primates, Marmost monkies. The study is conducted on anatomical MRI T1-weighted images. We aim to study the decline of brain and cortical volumes in normal aging.
However, due to the difficulty of extracting (segmenting) some cortical subregions, we would like to rather map the volumetric differences in these regions over years (due to aging / possible atrophy) rather than dileneating and extracting ROIs.
I would appreciate if some one could suggest a method (reference) or an algorithm to start with.
Frank Schmitz
Maybe this: Article MRT-basierte Morphometrie
could be a good entry point for finding the most appropriate way to solve this.
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