Hi Marwa, You must first find the appropriate pesticide's solvent and then stir the tissues in the solvent.Of course, for details, you should get help from an article in this area.
Your question should be more specific. Depending on the pesticides you get better results with different sample treatment procedures.
Generally speaking, the sample treatment will most likely involve an extraction to an aqueous matrix and SPE cleaning/concentration. You should look for specific information about your target pesticides.