For me, it is should be a quite important to start thinking about encouraging the emerging of the new world's builders, I mean the scientific entrepreneur profile.
the following study should be interesting for you as it contains empirical results to a very important part of your research question:
D’Este, P./Mahdi, S./Neely, A. (2010): Academic Entrepreneurship: What are the Factors Shaping the Capacity of Academic Researchers to Identify and Exploit Entrepreneurial Opportunities? DRUID Working Paper No. 10-05, Aalborg 2010
I believe the challenges of coupling "scientific research" and "entrepreneurship" are very great. If one uncouples them, a scientist can develop a product that he can then attempt to position in the marketplace; and an entrepreneur can uses the money he or she has made in business to fund his or her scientific research. But both simultaneously may dilute one's enthusiasm for both.