How can i calculate the cumulative drug release?

23 July 2019 1 5K Report

The in vitro drug release profiles of the beads were followed in simulated gastric and intestinal fluid. without mechanical stirring at 37∘ C. At predetermined time intervals, 0.7 mL of the samples was withdrawn and replaced with fresh medium. The drug content was determined by uv .

Muhammad Saad Khan

Cumulative means adding up. So after you take the second reading, the content of drug is added to first reading. After 3rd reading, you will add the content of all three and so on. This gives you a curve which reaches saturation point depending on the type of drug carrier you have employed.

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