How can I assess the carryover effect in a crossover RCT?

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Hongyang Ma

https://www.lexjansen.com/pharmasug/2006/Posters/PO16.pdf

DOI: 10.3238/arztebl.2012.0276

Gordon L Warren

If the treatment order is randomized among subjects, then a carryover effect can be controlled for.

The statistical test you use doesn't "assess" the carryover effect. A repeated-measures ANOVA with a randomized treatment order controls for it.

Bhogaraju Anand

Sturdevant, S.G., Lumley, T. Testing for carryover effects after cessation of treatments: a design approach. BMC Med Res Methodol 16, 92 (2016). https://doi.org/10.1186/s12874-016-0191-6

https://www.ibm.com/support/pages/worked-example-simple-crossover-design