Can I alkylate (e.g. iodoacetamide) solvent exposed cysteines of a purified membrane protein??

I have purified a transporter membrane protein and want to perform a CPM assay to assess its melting temperature as apo- and with ligands. The melt scan results in steadily dropping curve while my...

26 September 2020 1,455 4 View

How do I compare various cox proportional hazard regression models in SPSS?

I have generated various models with an identical core of fixed covariates with each model differing only in the study covariate (a categorical variable that I change in each model by altering...

14 September 2019 2,397 2 View

Why in 211 MAX phase publications mainly Ti2AlC, Ti2AlN and Cr2AlC are considered?

There is a plethora of possible MAX phases, but from what i have seen, papers tend to focus mainly on those three. What about all the other ones? Are they experimentally not feasible?

12 March 2019 4,300 6 View

What does it mean if I find more than one STR in a sequence?

I used TandemRepeatFinder to find STRs in sequences I retrieved from Genbank and in some sequences the program has found more than one STR. What does this mean? In a sequence for example, some of...

30 March 2018 3,794 1 View

What is your opinion about Fritz Haber?

02 April 2017 6,948 1 View

How to aplpy periodic boundary conditions on a cubic rve of a cellular solid using ANSYS/APDL(any code,advice,example would be very useful)?

Any type of help (guidelines,advice codes,examples) would be much appreciated since i'm having a tough time applying PBC in Ansys(APDL).

04 July 2016 6,441 2 View

Can we use Busch theorem to find the beam radius and the Larmor radius at any axial position?

The question is fairly simple In the book "Gyrotrons: High-Power Microwave and Millimeter Wave Technology" from M. V. Kartikeyan, Edith Borie, Manfred Thumm, in page 107 a generalization of Busch...

21 May 2015 1,281 2 View

Is there a resource for the current Tree of Life, based on published research?

I need to access global phylogenies, going down to the species level if possible. Is there a resource that provides different resolutions of the Tree of Life, based on our current knowledge about it?

01 February 2014 6,647 7 View

Any suggestions for synchronizing TM4 Sertoli cells?

I've recently thawed a TM4 Sertoli cell line, which I'd like to stimulate with a specific substance, but before I do that I want to synchronize it by using a specific Hunger medium. I've read...

28 January 2014 1,877 3 View

If we were to consider a concept to be the irreducible quantum of consciousness, how can this be applied and used in Cognitive Neuroscience?

A concept is not a mere group of coactivating synapses or a pattern of neuronal activity. It is the recognizable awareness of this underlying event. I came to the realization that a concept may...

30 August 2013 8,109 34 View

Does the circuit modeling for planar monopole antennas using Foster canonical forms give good approximation?

Hi researchers, I am searching for some accurate way to do the circuit modeling of planar CPW-fed monopole antennas. I have gone through the literature where mostly circuit modeling is done using...

28 February 2021 7,016 1 View

Why cannot world and community leaders be gentle? Where did ethics of care go?

The whole world is in a mess and paused. We all are tired of seeing hypermasculinized and destructive leaderships all around us. This world has seen enough of the aggressive patriarchal social...

23 February 2021 292 7 View

How COVID-19 has affected mental health?

The pandemic has led to depression and anxiety and its negative effects shouldn't be ignored. However, it has also led some people to become more resilient! What do you think? Thank you.

21 February 2021 4,733 19 View

What is the most prevalent drug related problem in the developed countries?

Detecting the drug related problems is an important step in the pharmaceutical care plan

21 February 2021 5,421 3 View

Can I do two kinds of mixed method in explanatory research?

Dear distinguish professors and scholars, I have a research in measuring two kinds: think tank capacity and research impact on policy. Can I do two kinds of mixed methods in order to find, "Is...

20 February 2021 6,897 1 View

Can I follow Researchers from Teaching and testing areas?

I want Researchers from Educational Measurement and Evaluation, relating to teaching, learning , academic performance and test validation

18 February 2021 4,757 13 View

Can medicinal plants really play an inherent rule in the COVID-19 tackle?

Numerous scientific reports cited plant extracts with potential antiviral activity and even anti-COVID-19? Why these findings are neglected? I remember very well the warning released by the WHO to...

17 February 2021 2,141 9 View

What are your alternative data collection methods during the pandemic? What are the pros and cons?

Dear colleagues We are exploring possible data collection methods for environment and behavior research in the context of architectural environments. Have you conducted any Post Occupancy...

16 February 2021 2,575 4 View

How can I interpret a ratio variable?

Dear colleagues, I am running a regression in which I have the following regression FoodExp = 67.04 DepRatio +.....e My interest is in the interpretation of the coefficient on the dependency...

16 February 2021 2,058 2 View

Room Occupancy Calculation ?

15 February 2021 1,997 6 View