According to endosymbiosis or symbiogenesis theory primitive ancestors of cyanobaceria and alpha proteobacterium entered a primitive, larger ancestor of Eukaryotic cell. Both cyanobacteria and mitochondial ancestor through a probabilistic anomaly, fluke or some unknown means established a synergestic relationship of being the powerhouses of the cell.

Over the evolutionary process both mitochondria and chloroplast went under massive gene reduction (90-99 percent) as most of the gene clusters were transferred to the host nuclear genome.

part of my project is to evaluate the total gene clusters located in the nucleus of the plant cell required for genomic and proteomic maintenance of chloroplasts. After some research of my own I was able to find a few gene clusters for chloroplast function. But given the massive size of cyanobacterial genome and eventual yet massive loss of it through endosymbiotic gene transfers, is it possible that all the genes have been identfied ad sequenced or there remain some gene clusters that are yet to be uncovered.

(which is the most appropriate source of finding these gene clusters? research publications or gene sequencing softwares?)