Hi Rabie.

Interesting idea. What would be your hypothesis? Or else...what link do you expect between donors and recipients? Do you think that embryo quality could be different int cows with different level of SR?

Regards,

Jiri

Hi Jiri,

I am studying donor, embryo and recipient contributions to establishment of pregnancy after transfer of in vivo produced embryos. I found that first grade embryos from high SOV donors achieved higher pregnancy in recipient heifers, regardless of recipient P4 level at transfer, while second and third grade embryos from high SOV donors achieved lower pregnancy rates after transfer into recipients.

Unfortunately, I do not find any literature regarding this topic.

Rabie, I find it quite normal that pregnancy rate is lower when two and three grade embryos are transferred. I would agree with Pouya Dini that you can concentrate for example on AMH. However it is quite challenging to find some relationship between SOR in donors and PR in recepients because SOR and PR is influenced by sooooooo many factors.

I was studying SOR after treatment with two different superovulatory protocols and one of the things I found was that the response is very variable (this you can find in almost every paper related to superovulatory protocols).

Regards,

Jiri

I know that PR/ET is higher with first grade embryos.

The question now is why did FGE from high SOV cows achieve higher pregnancy rates when compared to FGE from low SOV cows??? and why this trend was inversed (if it is true to say) for SGE and TGE????

IS it possible that FGE from high SOV dominated SGE and TGE so that the latter two (SGE and TGE) were of lower developmental competence.

I think this finding requires further investigation of developmentally important genes as IGF2 and IGF2R genes. Thus, I am seeking the literature for possible findings. What is your opinion?????