We are trying to acutely minimize the severe effects of diffuse axonal injury, by using some hormones and/or precursor neural cells, but we need to know about any device able to induce such a brain injury in rats.
Kate M Lewis
The Marmarou model of diffuse traumatic brain injury, or weight drop impact acceleration model, is still commonly used and already well characterised:
A new model of diffuse brain injury in rats. Part II: Morphological characterization.
Foda MA, Marmarou A.
J Neurosurg. 1994 Feb;80(2):301-13.
The apparatus described is also not very complicated.
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