I am looking for documented (publications and/or databases) genomic differences specifically between mice of 129Sv versus 129/Ola substrains. Already done several searches with various combinations of keywords, but I most certainly missed info that may be available on top of what I got so far. Any help will be appreciated.
Are you looking for the genotypic difference or the sequence difference? The genotypic/phenotypic details can be found in the following
http://www.informatics.jax.org/mgihome/nomen/strain_129.shtml
for genomic information
https://www.ensembl.org/Mus_musculus_129S1_SvImJ/Location/Genome?ftype=DnaAlignFeature;id=Ola.129
https://www.ensembl.org/Mus_musculus/Search/Results?q=129S;facet_feature_type=;site=ensembl;facet_species=Mouse;page=1;perpage=10;facet_strain=Mouse%20129S1%2FSvImJ
Thank you, Abhijeet Singh. I am actually looking for data as close as possible to, for example, the seminal Simpson’s article: Simpson EM, et al - Genetic variation among 129 substrains and its importance for targeted mutagenesis in mice. Nat Genet. 1997 May;16(1):19-27.
What about the sanger database?
https://www.sanger.ac.uk/sanger/Mouse_SnpViewer/rel-1303
Thank you, Daniel. I wasn’t sure those data would help in our case, but I’ll look into it again. Regards.
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