Hello dear colleagues
biotechnology is a very broad field that every day makes important leaps in the world of science. What do you think about the studies of metabolomics, proteomics and microbiome.
I thank you for your considerations.
Amended on 18 September 2018
I must sadly and repeatedly say that MS and HPLC-MS are not the quantitative method (personal communication from a kind engineer of Shimadzu Co., Kyoto, Japan, via Telephone).
HPLC-photometric method, which is quantitative, will be still remaining due to uniquely obeying the Lambert-Beer's law (please see files "JCB fucoidan transport" and "Lysozyme by RP-HPLC").
Protein microsequencer with HPLC-photometric detection is also a quantitative method if proteins are covalently bound to the glass filter (please see file; "HepG2 fucoidan" and "JMBT alopecia").
The obtained reliable data should be handled with non-parametric statistics (please see file; Dr. Terentyeva Urine BIN). Our true biological data has no Gauss Distribution, and median instead of mean and range instead of SD (standard deviation) should be used.
According to me-
Metabolomics will explore the potentiality of prececion medicine in a great extent. Even if, you can find variety of drugs depending on the distinctive metabolic pathway.
Proteomics already have been studied in full a swing and will be continued in future to render its effectiveness in pharmaceutical, agricultural as well as medical sectors.
Microbiome on the other hand will be a great way to determine gut bacterial population and may prescribe taking probiotics instead of drugs for gut microbial diseases. Meanwhile, it will also be a tremendous way of determining ecological imbalence of microbial communities in pond, river, lake, soil etc. through metagemonic profilling.
Thanks
thank you very much for leaving your impressions about the theme
I consider that the world of omics is one of the most important advances in biochemistry, indisputably each one of them contributes valuable information that is interconnected. I believe that microbiome studies are the necessary tool to study the ecology of complex biological systems, for example the ruminal environment in ruminant animals is an integrated system of microorganisms very little studied as a whole. Within these animals, the bufalos stands out for its ability to carry out a better use of fiber, an aspect that is closely linked to its ruminal ecosystem. By means of the comparative microbiome studies between different ruminant species, the genes of the microorganisms responsible for this superiority can be sequenced and by means of recobinant techniques these genes can be inserted in animals such as cattle to contribute to improving the use of fiber, by only give an example.
I would appreciate if you could comment some examples.
thank you
Yes, you are right @Maryen Alberto. Studying microbial communities through metagenomics is an emmerging area of research. Hope, this papers can be useful to get to know details
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