I came along quite some papers in the field of biosignal processing which first apply a low-pass or bandpass filter to the recorded signals (to remove high frequency sensor noise, etc.) prior to spectral estimation. 

Does this make sense? If I know that for instance the heart rate is between 30 bmp and 200 bmp, why would I not just compute the power spectral density and then look for the max in that very window?

Wouldn't a frequency selective filters skew the estimate (due to roll off  and ripples in the pass band)?

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