Induction of hyper and hypothyroidism in rats by drugs (LT4 and carbimazole), is the protocol scientifically valid to study the effect of bioactive compounds against thyroid dysfunction?
(pharmacological and clinical study)
What do you exactly mean by thyroid dysfunction, dysfunction of the thyroid gland itself (hyperactive or hypoactive gland) or effect of abnormal thyroid hormone level (higher or lower than normal) on other organs? If the second, maybe yes.
Muhammad M Hammami it's about dysfunction of the thyroid gland itself (hyperactive or hypoactive gland) ... to prove the effect of a substance on thyroid dysfunction
The guideline outlines testing for thyroid dysfunction in patients , including pregnant women or women planning pregnancy, and the monitoring of patients treated for primary thyroid function disorders. It does not apply to the BC Newborn Screening Program. This guideline outlines testing for thyroid stimulating hormone (TSH), free thyroxine (fT4), free triiodothyronine (fT3) and anti-thyroid peroxidase (TPO).
Information on other tests, including thyroglobulin/antithyroglobulin (Tg/anti Tg) and antibodies to the thyroid stimulating hormone receptor (TRAb), are covered in the associated BC Guideline
- Badges
- Science topic
- Similar topics
- Chemistry
- Pharmacology
- Pharmaceuticals
- Drugs