Exergy is available energy, defined precisely & quantitatively similar to entropy & related to entropy, not statistiacally, but operationally. Nanobioprocesses are our attempt at imitating what nature has wrought through aeons of evolution, homing in on the most efficient solution for a given purpose, not once, but many times. For example, wings came about at many different points of the evolutionary path. Instead of going for wasteful quick fixes, we need to simply & directly go to more efficient solutions. Use of exergy will help us to do this.