Do metal particles react with the end groups of dendrimers through covalent bonds or solubilize into dendrimers by encapsulation? The correlation characterization results!!!!
Dear Researcher,
For metal nanoparticles, it is better to encapsulate in dendrimers than conjugate covalently, since the loading efficiency of metal nanoparticles in dendrimers would be much more than covalently conjugated metal nanoparticles. on the other hand, if you want to use the covalently conjugated method, you should use surface modification and/or linkers for successful binding efficiency between two nanoparticles.
Many thanks,,
I fabricated nano dendrimer that it modified with linker and ligand, but I do not know by what mechanism the metal loaded in the next step !. And how can I prove this?
So the question is that, Do you want to conjugate metal nanoparticles to dendrimers covalently or load them in? If you want to load metal nanoparticles in dendrimers, you can simply use organic solvents, such as ethanol or DMSO or DMF, as a medium for loading nanoparticles in dendrimers at toom temperature, stirring at 60 rpm to 70 rpm, and if it is needed, dark conditions. Remember, it is necessary to be assured about the appropriate solubility of metal nanoparticles before adding them to the dendrimer solution.
I synthesized the dendrimer with a ligand and submitted to journal, and the reviewer asked me to prove that the metal solubilize to dendrimer by encapsulation or through a covalent bond to ligand?. Do you know how to prove each of them? how chracterized to prove them?
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