Now a days scientists are discovering so many bioactive principles from different plants...I am doing my main project on Withania somnifera and concentrating on withaferin.. But the bioactive compound ie discovering is not yet developing as a drug.I have heard only few examples like camptothecin which is used for treating cancer.So what are the hurdles that we are facing in India to develop a bioactive compound in drug form? Even the research institutes are only concentrating on analysis level and not intended to commercialise it by clinical trials. So share your opinion and the need for drug development of bioactive compounds.
You are perhaps misinformed. Please visit the web sites of CDRI , IMTech Chandigarh, Join OSDD group on google and drug discovery group on LINKEDIN.com. You will come to know all the answers
Ravi Sharma is right, and to Mini MS besides these website you will find many other on Google. There are reputed companies specialized in making medicines in particular and drugs and for beauty creams and lotion in general are extracting and purifying the bio-active products from the plants and either using those in their own manufactures medicines or selling to meet and cater the need of other firms.
There are many alkaloids and and other bio active products and plant extracts from various plants in India and abroad. There are some firms which are engaged only in extracting the extracts from plants that they sell to the manufacturers, be they use those foe cosmetic products or medicines. There are drug and medicine manufacturing firms that extracts and use those fo rtheir own products.
Yes, It is there. Importers in Developed countries are importing plant extracts for cheap from INDIA and selling finished products/formulations back to us + a cost rider. I just wonder, why India allows export of plant extracts/essential and aromatic oils as raw materials to developed countries pharma sector. I feel those companies should be asked to setup their plants in INDIA only. So that we get the drug on reasonable cost in INDIA itself
Sir i too visited 2 'SENNA' medicinal plant exporting companies in tamilnadu..They are actually exporting the powders n extracts of plants to various foreign countries.Sir i too agreeing with u .Because those multinational companies are selling finished product in developing countries like India.
it will be very interesting to threat some cancer cells and analyze with microarrays analysis the effects, and using reverse engineering technology which is the pathways involved. I have already used this technics in drug discovery and i think it will be very useful for your research too.
When you talk about medicinal plants as treatment under AYURVEDA. Plant based preparations can cure the disease, stimulate immunomodulatory system of the body to keep the body fit, a balanced intake of herbals can keep a number of ailments away[Preventive, therapeutic & curative], I know about some herbal preparations which prevent Cancer cells to certain extent. Only we have to potentiate it further and verify & validate the impact. There is a plant in MP, the leaf extract intake once in a year keeps malaria at bay for almost one year. For testing these remedies through modern medicine system, we have to work hard to find out suitable test models. There is adire need to develop new test models from Ayurveda point of view.
Besides the extracts and concoctions of the medicinal plants, there are many companies, the drug manufactures and others that make the alkaloids and the like chemicals including the colors and toxicants from the plants and the collection of herbs is a big business where the the herbs are dug or collected from the forest and now a days there have started medicinal plant cultivation also.
the interesting think would be testing in vitro or in vivo and performing microarrays analysis. After that starting from microarrays technics is is possible with reverse engineering technics and bayesian algorithms understand the patways and then validate only the predicted connections.
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