John Perry (Philosophy Talk) argued that having the uncertainty relations or QM a necessary condition for the Big-Bang sounds like a theology.
For Krauss' thesis on a pedestrian level see: https://www.radcliffe.harvard.edu/news/radcliffe-magazine/universe-nothing
For the Gettier problem - Knowledge as Justified True Belief (http://plato.stanford.edu/entries/epistemology/#JTB). Quote: "Cases like that- known as Gettier-cases[5], arise because neither the possession of evidence nor origination in reliable faculties is sufficient for ensuring that a belief is not true merely because of luck.".
In particular, does Heisenberg's uncertainty constitute "luck"?