Does HCl , NaOH and Water shows any peak in force degradation study in hplc?

More Charu Pandya's questions See All

Impurity profiling using HPLC and HPTLC?

During stability indicating method with HPLC and HPTLC, is it necessary that no. degradation products formed in HPLC should be same as that in HPTLC?

08 September 2018 3,305 0 View

Why there is pressure fluctuation and retention time in HPLC?

Respected Sir, I am doing method development.pKa of drug is 10.24. Column I am using YMC Pack Pro C18 250 mm in length and 3 micrometer in size. on one run of 100 ml of mobile phase pressure is...

01 February 2017 6,669 6 View

What is the reason of fluctuation in retention time in hplc?

Please find the details attached along with

31 December 2016 7,062 1 View

Whenever we prepare dilutions we prepare in 10 ml volumetric flasks. This dilution how can be prepared using eppendroff tubes?

Any one

05 June 2016 5,560 5 View

How to set mobile phase in gradient hplc in stability indicating method?

Saranjit Singh Vishal Pande

04 May 2016 961 6 View

Isolation of impurity techniques?

If we want to isolate impurity, in case preparative HPLC is not available whether impurity can be isolated using analytical column ( 250 mm* 4.6, 5 micron, 20 microlitre injector valve)for...

01 January 1970 6,811 6 View

Why there is pressure fluctuation in hplc? how to overcome this?

I am doing method development. on one run of 100 ml of mobile phase pressure is 190kgf, second run of 100 ml of measuring cylinder of mobile phase pressure is 150 kgf, third run 120 kgf. This...

01 January 1970 4,429 9 View

• What the possible Persistent Organic Pollutants and Heavy metals present in fluorspar, sediments, and water bodies around its mining area?

Approximate concentrations are require in compared with the WHO permissible limts

11 August 2024 2,723 1 View

Handling Missing Data and Building a Predictive Model with Incomplete Information ?

I am developing a predictive model for a water supply network that involves 20 influencing points. However, I only have historical data for 10 out of these 20 points. I would like to know how to...

10 August 2024 4,005 2 View

Do interactions between biosphere, carbon cycle, & water cycle impact global warming & interaction between atmosphere & hydrosphere?

How do interactions between the biosphere, the carbon cycle, and the water cycle impact global warming and interaction between the atmosphere and the hydrosphere?

09 August 2024 3,291 2 View

Is it true that $\det(V(A))$ may be only $\pm 1$, depending on $n$, for the last symmetric tridiagonal matrix $A$?

One can try to generalize the Vandermonde determinant in the following direction: Let $A$ be any symmetric $n$-order square matrix. Consider its powers' diagonal elements $(A^k)_{ii}$ and...

08 August 2024 6,690 1 View

How to increase simulation box size?

We intend to study the interaction between peptides and polymer (like PP, PE and PS) through MD simulations using Martini force fields ( Martini 2 for PP and Martini 3 for PE, PS). We have...

08 August 2024 4,842 0 View

How to Add Missing Water Molecules in Protein-Membrane Simulations?

I have protein-membrane simulations (PDB, PSF, DCD) and have noticed that water molecules near the protein are not visible in the simulations. How can I fix this issue? Is there a way to place the...

04 August 2024 1,200 2 View

The Optimal Experimental Approach for Gene Function Analysis?

What is the most suitable experimental setting to understand the consequences of a particular gene: (1) targeted degradation of the specific transcription factor (TF) of the gene, followed by...

04 August 2024 6,265 1 View

Why is nonpoint source pollution potentially more harmful and difference between point and nonpoint sources of water pollution?

01 August 2024 1,180 2 View

Melt curve problem in qPCR?

Do these peaks in the curve indicate primer dimer or non-specific products?

01 August 2024 7,466 0 View

How do living organisms play a role in the water cycle and why is nonpoint source pollution potentially more harmful than point source pollution?

01 August 2024 7,061 2 View