It is well established that Glut5 transports fructose in tissues like intestine, kidney and muscle. Does anyone know a publication describing other functions of Glut5 beyond that or other substrates, which can be shuttled by Glut5?
Article Targeting of GLUT5 for Transporter-Mediated Drug-Delivery Is...
I'm not sure if this helps but this article mentions using the Glut5 transporter to deliver drugs targeted to cancer cells.
Article D-Allulose is a substrate of glucose transporter type 5 (GLU...
Found this other article that shows D-Allulose is able to use the Glut 5 transporter
Thanks a lot!
GLUT 5 and diabetes.
Rats with type 2 diabetes had a dramatic increase in GLUT5 mRNA and protein levels in the kidneys.
Rats with diabetes also had a 3-4-fold increase in GLUT 5 mRNA and protein level in the small intestine
Rats with diabetes had a 2-3 fold increase in GLUT5 mRNA and protein levels in adipose tissue.
Humans with diabetes had a dramatic increase of GLUT5 mRNA and protein levels in skeletal tissue.
Cell Glucose Transport and Glucose Handling During Fetal and Neonatal Development
Rebecca A. Simmons, in Fetal and Neonatal Physiology (Fifth Edition), 2017
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