Free Cholesterol has a "terminal" metabolism and do not produce energy; however, esterified cholesterol can release 1 fatty acid, thus producing energy. In any case the actual contribute to body energy expenditure is very (very) little. In the diet, the total amount of cholesterol (FC + EC) is between 100 to 1000 mg (mean in north american about 450 mg/dye) so the FA-Chol linked can contribute for less than 0,1% !

Dear Rajib,

attached you will find an article that could be suits to your inquiry.

Regards,

Abraham

Thanks Dr. Abraham. Actually I am in search of a article where it is mentioned that cholesterol does not contribute to calorie content in diet. 

Dear Rajib,

Thank you for your question. Sources of energy in human body are carbohydrates, proteins, fats, and water soluble fibre that give little calories through fermentation then produce short chain fatty acids that enter the citric acid cycle through hepatic portal vein. Cholesterol is metabolized  to involve in forming more compounds that more important than giving energy, our body understand more biochemistry than us.

Best regards

Aly R Abdel-Moemin

Thanks Dr. Abdel-Moemin. 

Free Cholesterol has a "terminal" metabolism and do not produce energy; however, esterified cholesterol can release 1 fatty acid, thus producing energy. In any case the actual contribute to body energy expenditure is very (very) little. In the diet, the total amount of cholesterol (FC + EC) is between 100 to 1000 mg (mean in north american about 450 mg/dye) so the FA-Chol linked can contribute for less than 0,1% !

Thanks Dr. Gaddi. 

No at all or very little. Production of Cholesterol is not depend of total energetic input than synthesis in liver and resorption from digestive tract and it is genetic caused...

Rajib,

From comments of Antonio and Aly you know one half of the story. For the other half, you need to consider how much energy it takes to produce cholesterol that all cells need, given that there has been more than ample information for decades that in the presence of dietary cholesterol, endogenous synthesis of cholesterol reduces.

Dear,

Dietary cholesterol has very little impact on blood cholesterol levels in about 75% of the population. Dietary cholesterol does modestly increase both LDL (“bad cholesterol” and HDL (“good cholesterol”), but it does not affect the ratio of LDL to HDL or increase the risk of heart disease. (Djoussé L and Gaziano JM. Dietary cholesterol and coronary artery disease: a systematic review. Curr Atheroscler Rep 2009;11(6):418-22)

see this paper:

http://www.ncbi.nlm.nih.gov/pubmed/18726564

Dear Kazemi, you are right. The total phenotypic variance of LDLc (in humans) is about 18-20% (including dietary habit, environmentoma and other...), Lp(a) TPV il lower (5%, with some exceptions) (VLDL VLDLsd LDLsd HDL : ...omissis....) The problem is complex. About 400 papers were published on this matter, with different results. Differences in TPV exists between individuals, populations, etc. However, some authors suggested to calculate che CSI (cholesterol saturated index) for evaluation of plasma LDLc changes after diet. (in CSI formula, the valute of coefficient for dietary  cholesterol is 0,05 while for diet saturated fats is 0,95 !!!!). However CSI formula is not valid for all individuals and all populations....

Dear Alam: the cost (in terms of energy) for the synthesis of various compounds (and in a broad sense, for all biochemical reactions, including the futile cycles) is included in the "daily energy expenditure." The "Paul question" was about intake of calories, not on energetic expenditure.

As you rightly said, if we analyze the "whole" problem, we need to calculate the specific energy balances. What very difficult, in particular if it refers only to the metabolism of cholesterol. Determining factors are age, the mass / area ratio, physical activity, the thyroid state, the tissue/organ studied, n, n1, n2, nn ......omississ ......: there are dozens of factors that may change the metabolic cost specific. It is very difficult to have correct experimental data form single-cell (ex vivo, in vitro) ecc study; it is perhaps impossible at present to measure all the variables in a "free lining" human. So, usually we prefer to estimate the Total caloric balance or other simple measures

Antonio:

"Dear Alam: the cost (in terms of energy) for the synthesis of various compounds (and in a broad sense, for all biochemical reactions, including the futile cycles) is included in the "daily energy expenditure." The "Paul question" was about intake of calories, not on energetic expenditure."

Because one may chose to look at biological systems in a way where half of the story seems adequate, does not alter the law of conservation of energy.

Dear Rajib:

Review the publication "FATS AND FATTY ACIDS IN HUMAN NUTRITION" by the FAO, the link is:

http://www.who.int/nutrition/publications/nutrientrequirements/fatsandfattyacids_humannutrition/en/

Dear Dr. Villanueva,

Your attached file is very helpful for me. Thanks.

All researchers ! Carefully read the book of Claudio Galli and other authors cited by Javier: is precious !

AVG

Cholesterol contributes in calories. I am attaching reference.

Free cholesterol can produce little amount of energy, because during converting free cholesterol into androgen, we can get branched chain fatty acids called isocaproic acid and acetate that can produce energy

Il problema è di natura quantitativa !! In qualunque reazione biochimica PUO' esserci apporto o liberazione di energia. Il fatto è che le quantità di colesterolo alimentare (milligrammi/die) anche se prendono una strada che consente la produzione di energia (esempio: CE che libera un FA...) le quantità di energia prodotte sono irrisorie (e difficilmente misurabili in vivo nell'uomo). Come ordine di grandezza