Does anyone tried to perform palladium catalyzed decarboxylative cross-coupling?

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Pratik Ambasana

Hello Enrico,

Yes. We have worked with such reactions. Many references are also available on Pd catalyzed decarboxylative couplings. Simple thumb-rule is that you will need elevated temperature to cleave CO2 with ease. I have tried many such reactions in MW, and it works even better.