Does anyone know the best method of preparing amides from carboxylic acid and phenyl isocyanate or thio phenyl isocyanate?

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Adel Amer

A wide variety of carboxylic acids in the form of their ammonium salts condense with aryl isocyanates in DMF at room temperature with loss of carbon dioxide to give the corresponding amides in high yield. See

---Kaname Sasaki and David Crich, Org. Lett., 2011, 13 (9), pp 2256–2259

Good luck

Obinna Chibueze Okpareke

Many Thanks Adel Amer