Hi Inna,

Invitrogen Antibodies (Thermo Fisher) has a mAb (1D6E1A8) that they indicate is cross-reactive with mollusks. Here are our listings for anti-COX4 Abs:

https://www.linscottsdirectory.com/antibodies?q=COX4

follow "more info" to supplier's datasheet.

Hope this helps.

Thank you, Russell - it does!

Inna

Hi

 in silico check of the sequence ( BLAST) may help as a preliminary step or could corroborate the interpretation of stain. Of course a mAb is more specific than a polyclonal. 

Good luck

Thanks, Carlo. Unfortunately, most AB producers do not publish their epitope which they used to generate the AB so it's hard to tell whether the same epitope might be present in oysters.