Does anyone have experience with in situ trapping (not reversibly) of chloride in a reaction?

10 May 2015 1 8K Report

Does anyone has experience with in situ trapping (not reversibly) of chloride in a reaction? The reaction performed in organic solvent and high temp.

Andrei Rogoza

Lipophilic salts of sodium can help. NaBF4 is most available and soluble in some organic solvents enough to exchange. NaCl have poor solubility or insoluble at all (in acetone - 3x10-5g/100g but in ethyleneglycol - 46.5g/100g). NaBF4 sould be used in slight excess . Principle is same as ionic liquids synthesis.

More expensive salts are NaPF6 , NaN(SO2CF3)2, NaBPh4 , NaIO4; silver salts of corresponding anions are ideal in results but seems too costly for industry. It is not full list but I hope that idea is clear.

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