I find either 3D shapes of the hippocampus or sliced views of the hippocampus depicting neurons and their projections. But does anybody know of a good 3-dimensional depiction of neurons in the hippocampus (DG, CA3, CA1) including their projections?
Start with Larry Swanson's work. Swanson and Cown 1977, autoradiographic study of hippocampus and connections.
Here the first unfolded map is reconstructed from slices along the longitudinal axis. This flat map is key to understanding distribution and density of connections. Injecting radio graphic dye in small locations and sacrificing several days later the spread of the dye follows the anterograde transport. So get a feel for distribution in adjacent fields as well as along longitudinal axis.
Skip forward to 1998 with David Amaral and Cynthia Dolorfo, j. Comp. neurol. Where similar unfolded Entorhinal maps are generated along with hippocampal maps and the anterograde tracer PHA-L is used to the same purpose.
Then coming up on 2007-2009. Meno Witter began to construct a number of computer generated models depicting the inter- and intra- hippocampal projections to and from different layers. Cataloging not only the location and connections but also the density. Check out the lab website in Trondheim Norway for relevant publications and some pics of the models.
http://www.ntnu.no/cbm/witter
Should be enough to get you started.
For a Mickey Mouse quick and dirty understanding check out my website ww.PageoNeuroplasticity.com under the hippocampus article. Has not been updated for quite some time, but easy intro.
Thank you very much for the links and references. I will check them out as soon as possible. I also like your website about the hippocampus. This is a nice short introduction.
A German group published some very pretty pictures in a journal article some time ago--sorry, that's not much help, but may be nice. Also search for hippocampus publications by Lei Wang (formerly at Washington Univ. in St. Louis, now at Northwestern)--one should have a nice picture.
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