The following is a list of functional groups in decreasing order of their negative inductive effect (-I): —NH3+ > —NO2 > —SO2R > -CN > -SO3H > -CHO > CO > —COOH > -COCl> -CONH2 > —F > —Cl > —Br > —I > —OH > —OR > -NH2 > —C6H5 > —CH=CH2 > —H.

According to this list, -NH3+ is much more electronegative than -NH2. When -NH3+ forms a salt bridge with an negatively charged acid, should that lower its negative inductive ability?

What about the opposite situation for an acid like -COOH? Would a salt bridge with a positively charged base increase its negative inductive ability?

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