I'm looking for an antibody that does not cross react with human nor detects human protein. Needs to be 100% murine species specific. Application in xenografts.
Targeting murine specific MHC molecules would probably be the best. They will vary depending on which murine species you are using, but they are typically identified as H-2(X) antigens for MHC class I and I-A(X) antigens for MHC class II, where the (X) will vary with species.
Should be no problem, we have plenty antibodies specific to rodents with no possibility to cross-react to human proteins. This is because we specialize in peptide antibodies so we can rule out cross-reaction at the level of design. Please send me your wish list and we can take it from there. Email to [email protected]
Thanks but looking for something more generic. I guess I should have mentioned that principle use would be by chromogenic IHC. Concerned that MHC molecule targets may be difficult to capture as I am not necessarily in control of sampling.