The neurons in the pontine nuclei have the axons which project to the purkinje cells. But I don't know whether the pontine nuclei have the projections direct to CEREBRAL cortex or not. Does anyone have data or suggestion?
the best way, today, to find out about projections is the allen brain project: (http://mouse.brain-map.org/). They work exately with conectivity.
Thank you, Arthur
Are there any known data of non-human primate, especially for efferent from pontine nuclei?
Sorry, but I don't.
I don't work with primates, so my background will not help you so much.
Hi Yoshiyuki,
There is a projection from basilar pontine nucleus neurons projecting to the grnular cells via the mossy fibers and then unto the Purkinjie cells in the cerebral cortex. There is also a direction projection from the basilar pontine nucleus to the deep cerebellar nuclei base on anatomical studies in literature. I have incomplete and unpublished optogenetics data on basilar potine nucleus neurons and it projection to the granular cells in the cerebral cortex
I hope this Information is helpful to you, thanks
I am not sure about pontine projections to the cerebral cortex. But the following link might give some relevant information.
http://www.ncbi.nlm.nih.gov/pubmed/1374872
Thank you, John,
I'm afraid that "Purkinje cells in the cerebral cortex" you mentioned is "Purkinje cells in the cerebellar cortex." Is that right?
Thank you John,
My original question is misleading, I think. Sorry for confusing you.
No Problem..... there might be indirect project to cerebral cortex too but take a look at this paper:
http://www.ncbi.nlm.nih.gov/pubmed/15661196
If you would include the pedunculopontine tegmental nucleus (PPT) in the Pons then there may be some direct projections to some of the sensory cortices and possibly the motor cortex based on rodent research.
Thank you, Nikolaos
Yes, I'm also interested in those broadly projection neurons.
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