Do we have any acetal or silly ether protection for cyclic 1,5 diols like what we have for 1,3 and 1,4 diols?

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07 August 2021 0 0 View

MD MOE RMSD

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07 August 2021 0 0 View

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16 June 2021 0 0 View

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16 June 2021 0 0 View

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16 June 2021 0 0 View

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Teodoro S Kaufman

"silly ether???" Having a protective group for a 1,5 diol will mean to make an 8-member ring (or larger). These are difficult to make. Sometimes it is preferable to use the same PG forr bot of them and sometimes to explote their different reactivities and differentially protect them.

Mehrdad Shadmehr

Thank you does any other protecting group able to do this?