I am working on an in-silico model on docking and hence wanted to know whether we can build other than online server . Any suggestions , is much appreciated !!!
Behind many web servers are programs whose source code is available for download, e.g. The ViennaRNA Web Services https://rna.tbi.univie.ac.at are based on
the Vienna RNA Package, basic RNA secondary structure analysis software.
the ALIDOT package for finding conserved structure motifs (add-on)
the barriers program for analysis of RNA folding landscapes.
A novice user who is mainly interested in getting the predictions will normally prefer to use the web server.
Frequently, having the programs installed locally enables the advanced user more flexibility, to e.g. tweak parameters to settings better suited to a specific problem, to automate the processing of a large number of different sequences, but using these programs locally requires a reasonably good familiarity with the UNIX/LINUX command line and command line scripting
Thank you for your valuable input @ Annemarie Honegger. I have downloaded the source code ,like you said I'll try to tweak for a variable perspective for intrepretation and analysis .