I am looking for a target atomization pressure of 2 bar in a buchi b290 for spray drying an aqueous solution containing IgG. Can someone guide me on what should be the air flow meter reading height (mm) or air flow rate and aspirator % to achieve this pressure? I referred the manual and it gives pressure drop values corresponding to the air flow rates (L/h) , is the pressure drop value same as the atomization pressure?
Dear Heta,
The atomization pressure is set in the Compressor or Air Pressure Source. For Spray Dryer BUCHI-290, Silent Air Compressors are usually used, where you set the pressure up to 8 bar or higher. Then, an Air Regulating Valve sets the atomization pressure at the desired value (for example, 2 bar). The set pressure at the compressor must be higher (for example, 8 bar) than the atomization pressure at which you desire to work (to work at a pressure below 6 bar). The airflow meter reading height (mm) regulates the airflow at the set pressure. I am sharing with you an image of an air-regulating valve and what a spray dryer buchi-290 looks like with this accessory.
Thank you Carlos Espinoza-González . I was thinking along the same line that you mentioned, however the technician at Buchi told me to look at the pressure drop values corresponding to air flow rates in a reference table in the manual (attached here), that left me a bit confused.
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