Dear Robert
I have tried GC-HS for detection of ortho dichloro benzene (ODCB) in dye sample. But i didn't get peak of STD ODCB by GC-HS. So i cant quantify ODCB in dye. Will you suggest any method of GC-HS. So that i can develop method for
GC-HS.
Just inject a solution of dye dissolved in a suitable solvent directly into the GC and see if you get a peak for odcb.
How did you do the headspace analysis? Was the dye dissolved in water or solvent?
The Boiling point of ODCB is 180 degree so i hve dissolved the dye sample in N,N Dimethyl acetamide and then analyzed the sample in GC-HS. but ODCB peak was no confirm from GC-HS analysis.
I suspect the ODCB is too soluble in the dmac. Will the dye dissolve in water? Have you tried adding odcb to dmac and seeing if you get a peak by headspace GC?
You have a partition of odcb between the solvent and the atmosphere above the solvent. If the odcb is very soluble in the solvent it will not get into the atmosphere above the solvent.
Can anybody suggest GC-HS method use for detection of ODCB in Dye sample.
Did you tried the headspace sample preparation method (such as HS-Single drop or solid phase microextraction)?
I think the sensitivity of HS-GC is not too much, but headspace sample preparation can increase the sensitivity of your analyses.
Can you suggest the solvent use in ODCB and dye sample for GC-HS analysis.
Prepare the sample (ODCB plus the dye) in a water miscible solvent such as the one you are using dimethylacetamide or acetonitrile. Spike a few microlitres of it to 1-2 mL of deionized water in a vial with silicon septum. Heat to about 50 degrees. Do headspace solid-phase microextraction with PDMS or other fibre using a regular method for extraction and for GC.
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